Vyvanse (lisdexamfetamine) is a prescription medication commonly used in Australia to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe binge eating disorder (BED). While Vyvanse is effective for these conditions, many patients and caregivers notice changes in appetite and weight during treatment. This blog post explores the relationship between Vyvanse and weight loss, its causes, risks, and how to manage it safely.
Does Vyvanse Cause Weight Loss?
Yes, Vyvanse can lead to weight loss, primarily due to its appetite-suppressing effects. The medication works as a stimulant, increasing levels of dopamine and norepinephrine in the brain, which can reduce hunger and sometimes increase metabolism. This effect is more pronounced at higher doses.
Clinical studies have shown that:
- In adults, about 3% to 4% of those taking Vyvanse experience weight loss.
- In children, weight loss occurs more frequently, affecting approximately 9% of patients.
- After four weeks of treatment, adults lost on average between 1.3 to 2 kilograms (2.8 to 4.3 pounds), while children aged 6 to 17 lost between 0.4 to 2.2 kilograms (0.9 to 4.8 pounds), depending on age and dosage.
It’s important to note that people taking a placebo (inactive treatment) in these studies generally gained weight, highlighting the appetite-suppressing effect of Vyvanse.
Vyvanse Is Not Approved for Weight Loss
Although weight loss can occur, Vyvanse is not approved or recommended for weight loss or obesity treatment in Australia or internationally. Its use is strictly for ADHD and binge eating disorder. Using Vyvanse solely for weight loss carries significant health risks and is strongly discouraged.
Weight Loss in Children: Special Considerations
Children taking Vyvanse are more vulnerable to weight loss and may experience slowed growth in height and weight. In clinical trials, children on Vyvanse showed a decrease in growth percentiles over one year, prompting doctors to monitor their height and weight regularly.
If growth suppression or significant weight loss occurs, healthcare providers may recommend a temporary break from the medication to allow catch-up growth or adjust the treatment plan.
Risks of Misusing Vyvanse for Weight Control
Using Vyvanse without medical supervision or for off-label weight loss can lead to serious health issues, including:
- Increased blood pressure and heart rate, raising cardiovascular risks
- Development of tolerance, requiring higher doses to achieve appetite suppression
- Potential for dependence or misuse due to its stimulant nature
- Nutritional deficiencies from inadequate food intake
- Negative impacts on mental health, including anxiety and mood changes
Managing Weight Loss While Taking Vyvanse
If you or your child is experiencing unwanted weight loss on Vyvanse, consider these strategies:
- Regular monitoring: Keep track of weight and appetite, especially in children.
- Dose adjustment: Your doctor may lower the dose to balance symptom control and side effects.
- Nutritional support: Work with a dietitian to ensure adequate calorie and nutrient intake despite reduced appetite.
- Meal planning: Establish regular eating schedules and include nutrient-dense foods.
- Alternative medications: If weight loss is problematic, your doctor might suggest other ADHD treatments less likely to suppress appetite.
- Physical activity: Maintain regular exercise to support overall health and muscle mass.
Summary
Vyvanse can cause weight loss in some Australians due to its appetite-suppressing effects, particularly at higher doses. While this side effect is more common in children and requires careful monitoring, Vyvanse is not intended or approved for weight loss purposes. Patients should always use Vyvanse under medical supervision, with regular check-ins to manage side effects and ensure healthy growth and nutrition.