Cetirizine is classified as a second-generation antihistamine, primarily used to treat allergic rhinitis (commonly known as hay fever), urticaria (hives), and various forms of dermatitis. It works by blocking histamine—a chemical released during allergic reactions—from binding to H1 receptors in the body. This action helps to ease symptoms such as sneezing, runny nose, itchy eyes, and skin irritation.
| Cetirizine HCL | Cetirizine 10 mg |
| Cetirizine TABLET | Cetirizine Antihistamine |
| Cetirizine dose | Cetirizine Dose for dogs |
| Cetirizine uses | Cetirizine Syrup |
| Cetirizine side effect | Cetirizine hydrochloride |
- What is cetirizine mainly used for?
- What is the best use of cetirizine?
- What are the benefits of taking Cetrizine?
- Can cetirizine make you sleepy?
- Who needs cetirizine?
- Is cetirizine safe for kidneys?
Unlike first-generation antihistamines like diphenhydramine, cetirizine is less likely to cross into the brain, which significantly reduces sedative effects. However, it’s worth noting that among second-generation antihistamines, cetirizine is more likely to cause drowsiness compared to loratadine or fexofenadine.
How Fast Does Cetirizine Work?
One of the reasons cetirizine is widely recommended is its fast onset of action. You can expect to feel relief within 30 minutes, and the effects typically last for up to 24 hours—making it convenient for once-a-day dosing.
Is Cetirizine Safe to Use?
Generally, cetirizine is considered safe for both adults and children in Australia. It’s available over-the-counter in 10 mg tablets and can also be found in syrup form for paediatric use.
That said, like all medications, it does come with potential side effects. The most common include:
- Drowsiness
- Headaches
- Dry mouth
- Abdominal discomfort
- Fatigue
In rare cases, more serious side effects such as irregular heartbeat (tachycardia) or swelling (edema) have been reported.
Cetirizine for Children and Pregnancy
Cetirizine is often used for children with allergies, but drowsiness can be more noticeable in younger users. For pregnant individuals, studies suggest that the medication is generally safe. However, it’s not recommended during breastfeeding because small amounts may pass into breast milk.
Withdrawal Effects: Itchiness After Stopping
An interesting and lesser-known issue with cetirizine is post-discontinuation itchiness. People who’ve taken the medication for extended periods (typically over six months) have reported generalized itching after stopping the drug. This side effect can be intense enough to interfere with daily activities, although it’s considered uncommon.
Currently, there’s no official guideline on how to taper off cetirizine to avoid this effect, so it’s best to consult a healthcare professional if you’re planning to stop after long-term use.