Gabapentin, commonly known by the brand name Neurontin, is a widely used medication in Australia for managing neurological conditions such as epilepsy and neuropathic pain. It has become a staple in treatment plans due to its effectiveness and relatively well-understood safety profile.
What Is Neurontin (Gabapentin)?
Neurontin contains the active ingredient gabapentin, which is primarily prescribed for:
- Partial seizures: Used as an add-on therapy in adults and children aged 3 years and older who have not achieved adequate seizure control with other anti-epileptic drugs.
- Neuropathic pain: Effective in treating nerve-related pain conditions such as postherpetic neuralgia (pain following shingles).
Neurontin capsules are typically orange, hard gelatin capsules imprinted with “Neurontin 400mg” and are available in various strengths including 100 mg, 300 mg, 400 mg, and 800 mg tablets or capsules.
How Does Neurontin Work?
Gabapentin works by affecting nerve signals in the brain and spinal cord. Although its exact mechanism is not fully understood, it binds to specific calcium channel subunits on nerve cells, reducing the release of excitatory neurotransmitters. This action helps stabilize nerve activity, which is beneficial in controlling seizures and alleviating neuropathic pain.
Usage and Dosage in Australia
- Epilepsy: Treatment usually begins with a low dose that is gradually increased to minimize side effects. Maintenance doses typically range from 600 mg to 1800 mg daily, divided into three doses.
- Neuropathic Pain: Dosing often starts at 100 to 300 mg at night and is titrated up as needed, with typical doses ranging from 900 mg to 2400 mg daily.
Doses are individualized based on patient response and tolerability. It’s important to take Neurontin exactly as prescribed by your healthcare provider.
Availability and Access
Neurontin is a prescription-only medication in Australia and can be obtained through pharmacies with a valid prescription. It is subsidised under the Pharmaceutical Benefits Scheme (PBS) for approved indications, making it more affordable for many Australians.
However, there have been periodic shortages of gabapentin products due to manufacturing issues, and during such times, pharmacists may offer alternative generic gabapentin brands.
Storage and Handling
Neurontin capsules should be stored below 30°C and kept in their original packaging to protect from moisture and light. The typical shelf life is around three years.
Important Considerations
- Always follow your doctor’s instructions regarding dosage and timing.
- Do not stop taking Neurontin suddenly without medical advice, as this can increase seizure risk or cause withdrawal symptoms.
- Inform your healthcare provider about any other medications you are taking to avoid interactions.
- Report any side effects or unusual symptoms promptly.
Summary
Neurontin (gabapentin) is a key medication in Australia for managing partial seizures and neuropathic pain. Its proven efficacy and availability through the PBS make it an accessible option for many patients. While occasional supply shortages may occur, generic alternatives are usually available. Always use Neurontin under medical supervision to ensure safe and effective treatment.