Ondansetron, often known by the brand name Zofran, is a prescription drug that is frequently used to stop nausea and vomiting brought on by radiation therapy, chemotherapy, or surgery. It functions by preventing serotonin, a natural chemical that can induce nausea and vomiting, from doing its job. Ondansetron is regulated by the Therapeutic Goods Administration (TGA) in Australia and sold under a number of brand names, including Zofran.
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- What is the generic name for Zofran?
- Do I need a prescription for Zofran?
- Is ondansetron safe in pregnancy in Australia?
- Is Zofran the same as ondansetron?
What is Zofran?
Zofran is a prescription medication used primarily to prevent and treat nausea and vomiting. It belongs to a class of drugs called 5-HT3 receptor antagonists, which work by blocking serotonin, a natural substance in the body that can cause nausea and vomiting. It is most commonly prescribed in Australia for: Chemotherapy-induced nausea and vomiting (CINV) Post-operative nausea and vomiting Radiotherapy-induced nausea Off-label: Hyperemesis gravidarum (severe morning sickness in pregnancy), though this use is approached cautiously. Zofran is available in several forms in Australia, including oral tablets, orally disintegrating tablets (ODT), and injectable formulations.
Availability and Regulation in Australia
Zofran is a Schedule 4 (S4) drug in Australia, which means a prescription is required to obtain it. Its use and control are supervised by the Therapeutic Goods Administration (TGA).
Even though generic ondansetron is more affordable and easily accessible, many doctors still prescribe Zofran, especially in hospitals.